Catwoman is the story of meek, mild-mannered artist Patience Philips, who works for Hedare Beauty, a mammoth cosmetics company on the verge of releasing a revolutionary anti-aging product. When Patience inadvertently happens upon a dark secret her employer is hiding, she is attacked and killed. But Patience is given a second chance - a second life in which someone not quite human resides. Someone with the strength, speed, agility and ultra-keen senses of a cat. With her newfound power, Patience becomes Catwoman, and sets out to stop Hedare's callous plan to unleash an appallingly dangerous product into the world.

性格害羞、敏感和溫柔的菲柏絲任職化妝品公司的平面設計部。一次不小心，柏絲錯誤的運用了公司內一種將要推出市面的抗老化產品，她發現這種抗老化產品的驚人秘密與陰謀，令她陷入前所未有的危機。在她最灰暗無助的時候，柏絲被拯救了。當她再次醒來之時，她發現自己的身體變得強壯了，步伐快速了，觸角更銳利了，瞬眼之間，柏絲似乎都擁有了所有貓的特質…